Evaluation of signal formation in local arterial input function measurements of dynamic susceptibility contrast MRI
نویسندگان
چکیده
منابع مشابه
Evaluation of signal formation in local arterial input function measurements of dynamic susceptibility contrast MRI.
Correct arterial input function (AIF) measurements in dynamic susceptibility contrast-MRI are crucial for quantification of the hemodynamic parameters. Often a single global AIF is selected near a large brain-feeding artery. Alternatively, local AIF measurements aim for voxel-specific AIFs from smaller arteries. Because local AIFs are measured higher in the arterial-tree, it is assumed that the...
متن کاملToward local arterial input functions in dynamic contrast-enhanced MRI.
PURPOSE To present a method for estimating the local arterial input function (AIF) within a dynamic contrast-enhanced MRI scan, based on the alternating minimization with model (AMM) method. MATERIALS AND METHODS This method clusters a subset of data into representative curves, which are then input to the AMM algorithm to return a parameterized AIF and pharmacokinetic parameters. Computer sim...
متن کاملDynamic susceptibility contrast MRI with localized arterial input functions.
Compared to gold-standard measurements of cerebral perfusion with positron emission tomography using H(2)[(15)O] tracers, measurements with dynamic susceptibility contrast MR are more accessible, less expensive, and less invasive. However, existing methods for analyzing and interpreting data from dynamic susceptibility contrast MR have characteristic disadvantages that include sensitivity to in...
متن کاملCorrection of arterial input function in dynamic contrast-enhanced MRI of the liver.
PURPOSE To develop a postprocessing method to correct saturation of arterial input function (AIF) in T1-weighted dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for quantification of hepatic perfusion. MATERIALS AND METHODS The saturated AIF is corrected by parameterizing the first pass of the AIF as a smooth function with a single peak and minimizing a least-squares error in f...
متن کاملAutomatic Determination of Arterial Input Function for Dynamic Contrast Enhanced MRI in Tumor Assessment
Dynamic Contrast Enhanced MRI (DCE-MRI) is today one of the most popular methods for tumor assessment. Several pharmacokinetic models have been proposed to analyze DCE-MRI. Most of them depend on an accurate arterial input function (AIF). We propose an automatic and versatile method to determine the AIF. The method has two stages, detection and segmentation, incorporating knowledge about artery...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2011
ISSN: 0740-3194
DOI: 10.1002/mrm.23120